Atomic Force Microscopy: Overview
Recent advances in technology have allowed us to study our world at molecular, even subatomic resolution. One of the devices in the forefront of such studies is the atomic force microscope (AFM). This is a relatively complex device with two major applications. It can be used for imaging of biological samples in near- physiological conditions at atomic- level resolution. The AFM can also be used as a force apparatus to measure forces of receptor- ligand interactions down to the single molecule level, acquire information about the mechanical properties of biological materials including cells, as well as to measure forces of protein folding/unfolding.
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